![]() You can learn more about how we ensure our content is accurate and current by reading our editorial policy. ![]() Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Since seizures and some AEDs can harm an unborn baby, it’s important to work closely with your doctors while pregnant. Approximately 35 percent of people with catamenial epilepsy have worse seizures during pregnancy. If you want to have children, tell your doctor so that they can take extra steps to minimize reproductive issues. Some AEDs can negatively affect fertility or the effectiveness of hormonal drugs. To properly manage seizures, take your medication according to your doctor’s directions. Here’s how catamenial epilepsy affects the following scenarios: Your seizure management plan will include: This involves developing a plan to manage your seizures. Otherwise, if the condition goes untreated, it can lead to brain damage and poor quality of life.įor the best outlook, you’ll need to work closely with your healthcare team. Since catamenial epilepsy responds poorly to AEDs, controlling your seizures requires a multilayered approach. People with catamenial epilepsy may also benefit from epilepsy surgery targeting the area of the brain where the seizures originate. This involves removing the ovaries, which completely stops menstruation and can provide relief. You may also be asked to follow a seizure diet, or a low-carbohydrate diet, like the modified Atkins diet. If certain foods trigger seizures, you’ll likely need to avoid them. A neurologist can help you choose the safest hormonal drug for your situation. Hormonal drugs might negatively interact with some AEDs. The best option depends on whether you have regular or irregular periods. gonadotropin‐releasing hormone (GnRH) analogues.This includes drugs to increase progesterone or reduce estrogen. Hormonal drugs are used in combination with AEDs. You might also have to take multiple AEDs. You may need to take higher doses when you’re most likely to have worse seizures. Some AEDs can alter levels of reproductive hormones, which may continue triggering seizures. This is due to the hormonal fluctuations that happen during the menstrual cycle. The first line of treatment is anti-epilepsy drugs (AEDs). Thus, its proconvulsant effects can cause seizures in a C2 pattern. The mechanism behind these effects is unknown.Įstrogen increases around ovulation. Unlike progesterone, estrogen has proconvulsant effects. It helps regulate the menstrual cycle and growth of the uterine lining. Right before menstruation the progesterone decreases faster than estrogen leading to more estrogen than progesterone which is what is thought to trigger pre-menstrual seizures.Įstrogen is the main reproductive hormone in people assigned female at birth. Increased estrogenĬ1 and C2 patterns are related to changes in estrogen. It also decreases during the luteal phase. However, progesterone drops just before and during your period. It helps make neurosteroids in the brain, which control the excitability of nerve cells. The hormone also has natural anticonvulsant effects. It thickens the lining of your uterus, which prepares your body for a fertilized egg. Progesterone is a hormone that increases after ovulation each month. The C3 pattern is caused by inadequate progesterone secretion during the luteal phase. The C1 pattern is sometimes due to changes in progesterone. But according to a 2019 study, it’s related to the hormonal changes that happen during the menstrual cycle. The exact cause of catamenial epilepsy is unclear.
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